Hydroxyacetic ester derivatives, preparation method and use...

C - Chemistry – Metallurgy – 07 – D

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C07D 495/04 (2006.01) C07C 309/66 (2006.01) C07C 309/73 (2006.01) C07D 221/00 (2006.01) C07D 333/00 (2006.01)

Patent

CA 2306409

The invention concerns (R)-sulphonyloxyacetic ester derivatives of general formula (I) in which R¿1? represents a benzyl group, C¿1?-C¿4? alkyl optionally substituted by one or several halogen atoms, or phenyl optionally substituted by one or several halogen atoms or by one or several linear or branched C¿1?-C¿4? alkyl groups or by a nitro group. Said compounds are intermediates in the synthesis of clopidogrel.

L'invention concerne des dérivés d'esters (R)-sulfonyloxyacétiques de formule générale (I); dans laquelle R1 représente un groupement benzyle, alkyle en C1- C4 éventuellement substitué par un ou plusieurs atomes d'halogène, ou phényle éventuellement substitué par un ou plusieurs atomes d'halogène ou par un ou plusieurs groupements alkyles, linéaires ou ramifiés, en C1-C4 ou par un groupement nitro. Ces composés sont des intermédiaires dans la synthèse du clopidogrel.

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