Hydroxyalkylquinoline ether acids as leukotriene antagonists

C - Chemistry – Metallurgy – 07 – D

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C07D 215/14 (2006.01) A61K 31/47 (2006.01) C07D 215/18 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01)

Patent

CA 2053208

Compounds having the formula I: Image are leukotriene antagonists and inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection.

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