Hydroxyamino-hydrocarbonphosphonic acid derivatives and...

C - Chemistry – Metallurgy – 07 – F

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260/452, 260/501

C07F 9/38 (2006.01) C07F 9/40 (2006.01)

Patent

CA 1091241

ABSTRACT OF THE DISCLOSURE New hydroxyaminohydrocarbonphosphonic acid derivatives are provided of formula Image wherein R1 is hydrogen or acyl, R2 is hydrogen, lower alkyl, ar(lower)alkyl or acyl, and A is lower alklene, lower alkenylene or hydroxy(lower)alkylene, or the ester at the phosphono group thereof or the salt thereof: processes for preparing the derivatives are also provided, the new derivatives possess strong antibacterial activity against both Gram-positive and Gram-negative bacteria including those of the genera Bacillus, Salmonella, Pseudonomas and Entcrobacter.

283566

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