Hydroxybutenolide derivatives, production and use thereof

C - Chemistry – Metallurgy – 07 – D

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C07D 307/56 (2006.01) A61K 31/365 (2006.01) C07D 307/60 (2006.01) C07D 307/62 (2006.01)

Patent

CA 1328109

ABSTRACT OF THE DISCLOSURE The present invention relates to a compound of the formula: Image (I) (wherein Y is a chemical bond, oxygen atom, phenyleneoxy, or oxyphenyleneoxy; R1 is hydrogen or hydrocarbon residue; and R2 is hydrocarbon residue having two or more carbon atoms), production and use thereof. The compound (I) has an anti- oxidation activity and activities of preventing or improving functional disorders due to biologically active oxygen species, thus being useful as a pharmaceutical agent for prophylaxis and therapy of disorders in the circulatory system.

545174

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