(-)-hydroxycitric acid for delaying gastric emptying

Details (-)-hydroxycitric acid for delaying gastric emptying (-)-hydroxycitric acid for delaying gastric emptying

A - Human Necessities

61

K

A61K 31/191 (2006.01) A61K 31/194 (2006.01)

Patent

CA 2580733

The inventors have discovered that food and pharmaceutical compositions containing (-)-hydroxycitric acid, its salts, amides and esters can be employed for delaying gastric emptying and increasing receptive relaxation for preventing and treating diverse conditions. The invention provides for HCA- containing compound useful to delay gastric emptying and increase receptive relaxation for preventing and treating diverse conditions, e.g., stomach ulcers, portal hypertension, liver dysfunction, diabetes and obesity. The invention provides methods for delaying gastric emptying and increasing receptive relaxation in individuals. The invention also provides methods of preventing or treating disorders or conditions related to aberrant gastric emptying and receptive relaxation.

Selon cette invention, il s'avère que des compositions alimentaires et pharmaceutiques contenant l'acide (-)-hydroxycitrique, ses sels, amides et esters peuvent être utilisées pour retarder la vidange gastrique et accroître la relaxation réceptive afin de prévenir et/ou traiter divers états. L'invention porte sur un composé contenant HCA et utile pou retarder la vidange gastrique et accroître la relaxation réceptive afin de prévenir et/ou traiter divers états tels que des ulcères de l'estomac, l'hypertension portale, les troubles hépatiques, le diabète et l'obésité. L'invention porte également sur de procédés visant à retarder la vidange gastrique et l'accroissement de la relaxation réceptive chez des individus, ainsi que sur des méthodes de prévention et/ou traitement de maladies ou états liés à la vidange gastrique et à la relaxation réceptive aberrantes.

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