Hydroxyethyl-azole compounds, their production and their...

Details Hydroxyethyl-azole compounds, their production and their... Hydroxyethyl-azole compounds, their production and their...

C - Chemistry, Metallurgy

07

D

260/313, 260/315

C07D 233/60 (2006.01) C07C 29/40 (2006.01) C07C 45/46 (2006.01) C07D 249/08 (2006.01) C07D 521/00 (2006.01)

Patent

CA 1128528

ABSTRACT OF THE DISCLOSURE The invention relates to hydroxyethyl-azole compounds and methods for their preparation. The compounds are useful pharmacologically as antimycotic agents. They correspond to the general formula (I) Image in which Az denotes an imidazole or triazole radical, R represents phenyl optionally mono or di-substituted by chlorine, fluorine or methyl, or represents naphthyl or tetrahydro- naphthyl, R1 represents phenyl or cycloalkyl optionally substituted by chlorine, bromine, fluorine, alkyl with 1 to 4 carbon atoms, or alkoxy with 1 to 4 carbon atoms, R2 represents hydrogen, or R1 and R2 together, in the o-position relative to one another, represent a polymethylene bridge optionally substituted by chlorine or methyl, or, together with the phenyl ring, represent naphthyl, R3 denotes a halogen atom or an alkyl, alkoxy or halogeno-alkyl group and n is 0, 1, 2 or 3.

340547

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