Hydroxyl-sustituted...

C - Chemistry – Metallurgy – 07 – C

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260/603.7

C07C 45/28 (2006.01)

Patent

CA 1057309

A B S T R A C T Hydroxyl-substituted 2-chloro-a-(tert-butylamino- methyl)-benzylalcohols of the formula Image (I) useful as bronchodilators. A method of manufacture comprises reducing the compound Image in the presence of tert-butylamine to produce the desired product (I). The intermediate is produced by oxidizing with selenium dioxide the compound Image

226033

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