Hydroxylamine derivative

Details Hydroxylamine derivative Hydroxylamine derivative

C - Chemistry, Metallurgy

07

C

167/242, 167/244

C07C 259/04 (2006.01) A61K 31/27 (2006.01) A61K 31/335 (2006.01) A61K 31/38 (2006.01) C07C 259/06 (2006.01) C07C 259/08 (2006.01) C07C 275/64 (2006.01) C07D 307/81 (2006.01) C07D 311/58 (2006.01) C07D 311/64 (2006.01) C07D 313/08 (2006.01) C07D 333/58 (2006.01) C07D 335/06 (2006.01) C07D 337/08 (2006.01)

Patent

CA 2024192

ABSTRACT This invention relates to new hydroxylamine derivatives having a 5-lipoxygenase inhibitory activity and represented by the general formula [I] : Image [I] wherein R1 is aryl, aryloxy, arylthio, ar(lower}alkyl or ar(lower)alkoxy, R2 is acyl, A is hydroxy or protected hydroxy, X is -CH2-, -O- or -S-, and n is an integer of 0 to 2, and pharmaceutically acceptable salts thereof, to processes for the preparation thereof and to a phanmaceutical composition comprising the same.

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