C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 239/70 (2006.01) A61K 31/517 (2006.01) A61P 35/00 (2006.01) C07D 401/12 (2006.01) C07D 403/04 (2006.01) C07D 403/12 (2006.01) C07D 407/12 (2006.01) C07D 409/12 (2006.01) C07D 409/14 (2006.01)
Patent
CA 2656622
The present invention provides compounds, including resolved enantiomers, resolved diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula (I). Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.
La présente invention concerne des composés répondant à la Formule (I), y compris des énantiomères résolus, des diastéréoisomères résolus, des solvates, et leurs sels pharmaceutiquement acceptables. La présente invention concerne également des procédés d'utilisation des composés en tant qu'inhibiteurs de la protéine kinase AKT et pour le traitement de maladies hyperproliférantes telles que le cancer.
Banka Anna L.
Bencsik Josef R.
Blake James F.
Chabot Christine
Do Steven
Array Biopharma Inc.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Genentech Inc.
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