Hydroxylation activated prodrugs

Details Hydroxylation activated prodrugs Hydroxylation activated prodrugs

C - Chemistry, Metallurgy

07

C

C07C 49/84 (2006.01) A61K 31/09 (2006.01) A61K 31/12 (2006.01) C07C 43/215 (2006.01) C07C 205/35 (2006.01) C07C 255/36 (2006.01) C07C 327/48 (2006.01) C07D 213/57 (2006.01)

Patent

CA 2319836

The present invention concerns enzymatic aromatic hydroxylation-activated prodrugs, particularly and-tumour prodrugs and those which are specifically activated by the hydroxylation activity of the enzyme CYP1B1.

La présente invention concerne des promédicaments enzymatiques, aromatiques, activés par hydroxylation, notamment des promédicaments antitumoraux et particulièrement ceux qui sont activés de manière spécifique par l'activité d'hydroxylation de l'enzyme CYP1B1.

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