C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 229/64 (2006.01) A61K 49/00 (2006.01) C07F 7/10 (2006.01) C07F 7/18 (2006.01) C07K 1/113 (2006.01) C07K 2/00 (2006.01) G01N 33/48 (2006.01) G01N 33/53 (2006.01) G01N 33/84 (2006.01)
Patent
CA 2219012
The invention disclosed relates to the novel compound 5-amino tetrahydroxy benzoic acid and derivatives thereof, e.g. pharmaceutically acceptable acid addition salts, to a process for the preparation thereof which involves reacting5-amino salicylic acid with hydroxyl radical, and to a method of using 5-amino tetrahydroxy benzoic acid and derivatives thereof as a biomarker for the presence of hydroxyl radical in biological systems.
Cette invention concerne un nouveau composé, l'acide 5-aminotétrahydroxybenzoïque, et des dérivés de celui-ci, des sels d'addition acides utiles en pharmacie. Elle concerne aussi un procédé de préparation de ces composés, comprenant la réaction de l'acide 5-aminosalicylique avec le radical hydroxyle, et une méthode d'utilisation de l'acide 5-aminotétrahydroxybenzoïque et de ses dérivés comme dépisteur biologique de la présence de radicaux hydroxyles dans des systèmes biologiques.
Kumarathasan Premkumari
Vincent Renaud
Anderson J. Wayne
Her Majesty The Queen In Right Of Canada As Represented By The Minister Of Health
Kumarathasan Premkumari
Vincent Renaud
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