C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 209/44 (2006.01) A61K 31/4035 (2006.01) A61K 31/422 (2006.01) A61P 13/00 (2006.01) A61P 25/00 (2006.01) C07D 413/04 (2006.01)
Patent
CA 2683584
The present invention is directed to certain hydroxymethyl ether hydroisoindoline compounds which are useful as neurokinin-1 (NK-1) receptor antagonists, and inhibitors of tachykinin and in particular substance P. The invention is also concerned with pharmaceutical formulations comprising these compounds as active ingredients and the use of the compounds and their formulations in the treatment of certain disorders, including emesis, urinary incontinence, LUTS, depression, and anxiety.
Cette invention concerne certains composés hydroisoindolines d'éther hydroxyméthyle qui sont utiles comme antagonistes du récepteur neurokinine-1 (NK-1) et inhibiteurs des tachykinines, en particulier de la substance P. L'invention concerne également les formulations pharmaceutiques comprenant ces composés comme ingrédients actifs et l'utilisation des composés et de leur formulation dans le traitement de certains troubles, y compris l'émèse, l'incontinence urinaire, les SBAU, la dépression et l'anxiété.
Bao Jianming
Devita Robert J.
Jiang Jinlong
Kassick Andrew J.
Mills Sander G.
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
LandOfFree
Hydroxymethyl ether hydroisoindoline tachykinin receptor... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Hydroxymethyl ether hydroisoindoline tachykinin receptor..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Hydroxymethyl ether hydroisoindoline tachykinin receptor... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1576110