Hydroxyomeprazole compositions and uses

Details Hydroxyomeprazole compositions and uses Hydroxyomeprazole compositions and uses

A - Human Necessities

61

K

A61K 31/4439 (2006.01) A61K 31/415 (2006.01) A61P 1/04 (2006.01)

Patent

CA 2330049

Methods and compositions are disclosed utilizing hydroxyomeprazole for the treatment of ulcers in humans. Hydroxyomeprazole exhibits a lessened liability toward drug-drug interactions than omeprazole and a more predictable dosing regimen than omeprazole. Hydroxyomeprazole is also useful for the treatment of gastroesophageal reflux and other conditions related to gastric hypersecretion such as Zollinger-Ellison Syndrome.

L'invention concerne des procédés et des compositions mettant en oeuvre l'hydroxyméprazole pour traiter des ulcères chez l'homme. Comparé à l'oméprazole, l'hydroxyméprazole montre une susceptibilité moindre aux interactions de médicaments et un schéma posologique plus prévisible. L'hydroxyméprazole est également utile pour le traitement du reflux gastro-oesophagien ou d'autres affections liées à une hypersécrétion gastrique telle que le syndrome de Zollinger-Ellison.

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