C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 231/12 (2006.01) A61K 31/415 (2006.01) A61P 35/00 (2006.01) C07D 401/04 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01)
Patent
CA 2470616
The present invention provides a method for treating diseases caused by and/or associated with an altered protein kinase activity which comprises administering to a mammal in need thereof and effective amount of o-hydroxy phenyl-pyrazol-3-yl derivatives optionally substituted of formula (I). The invention also provides some new compounds, a library comprising at least two of them, a process for their preparation and the pharmaceutical compositions containing them, which are useful in the treatment of diseases caused by and/or associated with an altered protein kinase activity such as cancer, cell proliferative disorders, viral infections, autoimmune diseases and neurodegenerative disorders.
La présente invention concerne un procédé pour traiter des maladies induites par et/ou associées à une activité modifiée de protéine kinase. Ce procédé consiste à administrer à un mammifère le nécessitant une quantité efficace de dérivés d'hydroxyphényl-pyrazol-3-yle éventuellement substitués de formule (I). La présente invention concerne également de nouveaux composés, une bibliothèque comprenant au moins deux de ces composés, un procédé pour les préparer et les compositions pharmaceutiques les renfermant, utilisées pour traiter des maladies induites par et/ou associées à une activité modifiée de protéine kinase, telles que le cancer, les troubles de prolifération cellulaire, les infections virales, les maladies auto-immunes et les maladies neurodégénératives.
Casuscelli Francesco
D'alessio Roberto
Felder Eduard
Vulpetti Anna
Pharmacia Italia Spa
Smart & Biggar
LandOfFree
Hydroxyphenyl-pyrazole derivatives active as kinase... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Hydroxyphenyl-pyrazole derivatives active as kinase..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Hydroxyphenyl-pyrazole derivatives active as kinase... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1863348