Hydroxyphenyl-thiazole-, -thiazoline- and -...

Details Hydroxyphenyl-thiazole-, -thiazoline- and -... Hydroxyphenyl-thiazole-, -thiazoline- and -...

C - Chemistry, Metallurgy

07

D

260/310, 260/308

C07D 277/12 (2006.01) C07D 277/06 (2006.01) C07D 277/56 (2006.01)

Patent

CA 1171420

HOE 80/F 014 HYDROXYPHENYL-THIAZOLE-, -THIAZOLINE- AND -THIAZOLIDINE- CARBOXYLIC ACIDS, THEIR PREPARATION AND THEIR USE FOR INFLUENCING THE COLLAGEN METABOLISM Abstract of the disclosure: The invention relates to hydroxyphenyl-thiazole-, -thiazoline- and -thiazolidine-carboxylic acids of the formulae Image Image (I) (II) in which R1 and R3, independently from each other, are hydrogen, methyl, chlorine or bromine, and R1 or R3 may alterna- tively be nitro, amino or sulfonylamido; R2 is hydrogen, hydroxyl or methyl; R4 is hydrogen or methyl; and R5 is hydrogen, methyl, phenyl or -COOH; and their salts with physiologically acceptable bases, a process for the preparation thereof and their use for influencing the collagen metabolism.

369496

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