Hydroxyphenylacetamides having analgesic and anti- irritant...

Details Hydroxyphenylacetamides having analgesic and anti- irritant... Hydroxyphenylacetamides having analgesic and anti- irritant...

A - Human Necessities

61

K

167/268, 260/552

A61K 31/165 (2006.01) C07C 103/76 (1985.01)

Patent

CA 1244473

NOVEL HYDROXYPHENYLACETAMIDES HAVING ANALGESIC AND ANTI-IRRITANT ACTIVITY Thomas R. LaHann Brian L. Buckwalter ABSTRACT A compound, or pharmaceutically acceptable salt thereof, having the formula: Image wherein R is a linear or branched C3-C11 alkyl, alkynyl or aralkyl group, a linear or branched C3-C22 alkenyl group, or an unbranched or branched C6-C11 cycloalkyl or cycloalkenyl group; and wherein one of R1 and R2 is OH, the other being OH or H. These hydroxyphenylacetamides have analgesic and/or anti-irritant activity when administered either topically or systemically.

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