Hydroxyproline-rich proteins and pharmaceutical and cosmetic...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/415 (2006.01) A61K 8/64 (2006.01) A61K 8/97 (2006.01) A61K 38/16 (2006.01) A61Q 19/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2208960

The invention relates to hydroxyproline-rich glycoproteins, which can be obtained by acid alcohol extraction from Taxus spp., Gingko biloba, Lycopersicum esculentum and Daucus carota cell cultures, having the following characteristics: average molecular weight 20,000 Daltons with variability interval 12,000 to 38,000, determined by means of gel permeation and electrophoresis; high solubility in water.

Glycoprotéines riches en hydroxyproline pouvant être obtenues par extraction d'alcool acide à partir de cultures cellulaires de Taxus spp., de Ginko bilboa, de Lycopersicum esculentum et de Daucus carota. Les glycoprotéines en question possèdent les caractéristiques suivantes: une masse moléculaire moyenne de 20 000 daltons, variant entre 12 000 et 38 000 daltons, déterminée par perméation sur gel et par électrophorèse; et une hydrosolubilité élevée.

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