C - Chemistry – Metallurgy – 07 – F
Patent
C - Chemistry, Metallurgy
07
F
C07F 13/00 (2006.01) A61K 49/08 (2006.01)
Patent
CA 2456161
The present invention provides hydroxypyridinone and hydroxypyrimidone chelating agents. Also provided are Gd(III) complexes of these agents, which are useful as contrast enhancing agents for magnetic resonance imaging. The invention also provides methods of preparing the compounds of the invention, as well as methods of using the compounds in magnetic resonance imaging applications.
La présente invention concerne des chélateurs d'hydroxypyridinone et d'hydroxypyrimidone. L'invention concerne en outre des complexes Gd(III) desdits agents, qui sont utiles comme agents de contraste pour l'imagerie par résonance magnétique. L'invention concerne en outre des méthodes de préparation desdits composés, ainsi que des méthodes d'utilisation de ces derniers dans des applications d'imagerie par résonance magnétique.
Doble Daniel M. J.
Raymond Kenneth N.
Sunderland Christopher J.
Thompson Marlon
Fetherstonhaugh & Co.
The Regents Of The University Of California
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