C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 15/203 (2006.01) A61K 31/70 (2006.01) A61K 31/7004 (2006.01) A61P 31/04 (2006.01) A61P 33/02 (2006.01) C07D 405/14 (2006.01) C07D 407/12 (2006.01) C07D 407/14 (2006.01) C07D 453/02 (2006.01) C07D 487/08 (2006.01) C07D 521/00 (2006.01)
Patent
CA 2410643
This invention relates to compounds of formula (1) and to pharmaceutically acceptable salts, prodrugs and solvates thereof, wherein R1, R2, R3 and R10 are as defined herein. The compounds of formula (1) are antibacterial and antiprotozoal agents that may be used to treat various bacterial and protozoal infections and disorders related to such infections. The invention also relates to pharmaceutical compositions containing the compounds of formula (1), methods of treating bacterial and protozoal infections by administering the compounds of formula (1).
L'invention concerne des composés de formule (1) et leurs sels pharmaceutiquement acceptables, ainsi que les promédicaments et solvates de ceux-ci, formule dans laquelle R?1¿, R?2¿, R?3¿ et R?10¿ sont tels que définis dans la description. Les composés de formule (1) sont des agents antibactériens et antiprotozooses pouvant être utilisés pour traiter diverses infections bactériennes et protozooses, ainsi que des troubles se rapportant à de telles infections. L'invention concerne également des compositions pharmaceutiques contenant les composés de formule (1), ainsi que des méthodes de traitement d'infections bactériennes et protozooses par administration des composés de formule (1).
Hayward Matthew Merrill
Kaneko Takushi
Linde Robert Gerald II
Visser Michael Scott
Pfizer Products Inc.
Smart & Biggar
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