Hygromycin derivatives

C - Chemistry – Metallurgy – 07 – H

Patent

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Details

C07H 15/26 (2006.01) A61K 31/70 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2389191

The present invention relates to compounds of formula (1) and to pharmaceutically acceptable salts, produgs and solvates thereof, wherein X, Y, V, W1, W2, Z1 and Z2 are as defined herein. The invention also relates to pharmaceutical compositions containing the above compounds and to methods of treating bacterial and protozoal infections in mammals by administering the above compounds.

La présente invention concerne des composés de la formule (1) et des sels, promédicaments et solvats pharmaceutiquement acceptables desdits composés. Dans ladite formule X, Y, V, W?1¿, W?2¿, Z?1¿ et Z?2¿ sont tels que définis dans le mémorandum descriptif. L'invention concerne en outre des compositions pharmaceutiques contenant lesdits composés, et des méthodes de traitement d'infections bactériennes ou protozoaires chez des mammifères par administration des composés de l'invention.

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