Hypoallergenic allergy vaccines based on the timothy grass...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/29 (2006.01) A61K 39/36 (2006.01) A61P 37/08 (2006.01) C07K 14/415 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2500234

The present invention pertains to polypeptides derived from the timothy grass pollen allergen Phl p 7. The polypeptides display reduced allergenic activity and are useful as allergy vaccines for treatment of sensitized allergic patients and for prophylactic vaccination.

L'invention concerne des polypeptides dérivés de l'allergène PhI p 7 du pollen de plante herbacée de type fléole des prés. Les polypeptides présentent une activité allergénique réduite et sont utilisés comme vaccins anti-allergiques pour le traitement de patients sensibles à des allergies et pour une vaccination prophylactique.

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