Hypoallergenic molecules

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/415 (2006.01) A61K 39/36 (2006.01) C12N 15/29 (2006.01)

Patent

CA 2696691

The present invention relates to a hypoallergenic molecule consisting of Bet v Ia or an allergen having at least 40% identity to Bet v la comprising mutations of at least four amino acid residues in the region of amino acids 100 to 125 of Bet v Ia or its corresponding region of the allergen having at least 40% identity to Bet v 1a.

La présente invention porte sur une molécule hypoallergénique consistant en Bet v 1a ou un allergène ayant au moins 40 % d'identité avec Bet v 1a, comprenant des mutations d'au moins quatre résidus d'acide aminé dans la région des acides aminés 100 à 125 de Bet v 1a ou sa région correspondante de l'allergène ayant au moins 40 % d'identité avec Bet v 1a.

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