Hypoallergenic polypeptides based on fish parvalbumin

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 31/7088 (2006.01) A61K 35/12 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) A61P 37/08 (2006.01) C07K 14/46 (2006.01) C12N 15/63 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2475073

The present invention relates to non-naturally occurring polypeptides derived from fish allergens such as parvalbumin Cyp c 1.01 from carp. The polypeptides display reduced allergenic activity and are useful as allergy vaccines for treatment of sensitized allergic patients and for prophylactic vaccination.

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