Hypoglycaemic peptides

Details Hypoglycaemic peptides Hypoglycaemic peptides

C - Chemistry, Metallurgy

07

K

530/7.02, 530/7.

C07K 7/04 (2006.01) A61K 38/04 (2006.01) C07K 5/02 (2006.01) C07K 14/61 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1341270

A compound of general formula I: Image wherein X is hydrogen, -CHCONH2 or -CH2CH2CONH2; each of R1, R2 and R3 is an L-.alpha.-amino acid, a .delta.-amino acid or an .epsilon.-amino acid; R4 is an L or D .alpha.-amino acid, a .delta.- amino acid or an .epsilon.-amino acid; and each of R5 to R11 is hydrogen or an L or D a-amino acid, a .delta.-amino acid or an .epsilon.-amino acid, or a pharmaceutically acceptable salt thereof. Methods of synthesis of peptides according to general Formula I, compositions containing the peptides, and uses of the peptides are also disclosed and claimed.

581850

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