Hypoglycaemic phenylamidines and phenylguanidines

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 295/155 (2006.01) A61K 31/395 (2006.01) C07C 257/10 (2006.01) C07C 279/18 (2006.01) C07D 207/22 (2006.01) C07D 211/72 (2006.01) C07D 223/12 (2006.01) C07D 225/04 (2006.01) C07D 233/50 (2006.01) C07D 295/13 (2006.01) C07D 295/135 (2006.01) C07D 401/12 (2006.01) C07D 413/10 (2006.01)

Patent

CA 2006577

Compounds of formula I (see formula I) and their salts in which n = 0 or 1, R1 and R2 are each aliphatic or cycloalkyl or NR1R2 is an optionally substituted heterocyclic ring, R3 is alkyl, cycloalkyl or optionally substituted amino, R5 is an aliphatic group, R6 is H, an optionally substituted aliphatic group or a cycloalkyl group, or R3 and R5 together with the nitrogen and carbon atoms to which they are attached form an optionally substituted heterocyclic ring or R5 and R6 together with the nitrogen to which they are attached form a heterocyclic ring optionally substituted by alkyl and R7 is optionally substituted alkyl, alkoxy, alkylthio, alkylsulphinyl, alkylsulphonyl, alkoxycarbonyl, trifluoromethyl or cyano have utility as hypoglycaemic agents.

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