A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
167/234, 167/237
A61K 31/14 (2006.01) A61K 31/415 (2006.01) B05B 15/04 (2006.01)
Patent
CA 2036902
ABSTRACT OF THE DISCLOSURE The present invention relates to pharmaceutical compositions containing at least one of hydantoin derivatives as hypoglycemic as well as hypolipidemic agents. The present invention is based on the selection of a hydantoin which is bonded by a sulfonyl group to various substituents at the 1 - position of the hydantoin skeleton. The compounds of the present invention represent a satisfactory hypoglycemic as well as hypolipidemic activity. These compounds are extremely useful for the treatment and/or prevention of diabetes mellitus with or without hyperlipidemia. It is indicated that the compounds of the present invention are useful for the treatment and/or prevention of diabetic complications such as somatic or autonomic neuropathy, cataract, retinopathy, nephropathy or microangiopathy. It is also indicated that the compounds of the present invention are useful for the treatment and/or prevention of hyperlipidemia.
Kato Katsuaki
Kato Kazuo
Miwa Ichitomo
Mochida Ei
Murakami Kimihiro
Borden Ladner Gervais Llp
Mochida Pharmaceutical Co. Ltd.
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