C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 281/10 (2006.01)
Patent
CA 2117485
The present invention is concerned with compounds of formula (I) wherein 1 is an integer of from 0 to 4; m is an integer of from 0 to 5; n is an integer of from 0 to 2; R and R' are atoms or groups; independently selected from halogen, nitro, phenylalkoxy, C1-4 alkoxy, C1-6 alkyl and -O(CH2)pSO3R" wherein p is an integer of from 1 to 4 and R" is hydrogen or C1-6 alkyl, wherein said phenylalkoxy, alkoxy and alkyl groups are optionally substituted by one or more halogen atoms; R4 is a C1-6 straight alkyl group; and R5 is a C2-6 straight alkyl group; and their salts, solvates and physiologically functional derivatives, with processes and novel intermediate for their preparation, with pharmaceutical compositions containing them and with their use in medicine, particularly in the prophylaxis and treatment of hyperlipidaemic conditions, such as atherosclerosis.
Ogilvy Renault
The Wellcome Foundation Limited
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