C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 281/10 (2006.01) A61K 31/55 (2006.01)
Patent
CA 2317651
The invention is concerned with novel hypolipidemic compounds of formula (I), wherein R1 is H or methyl, and salts, solvates or physiologically functional derivatives thereof, with processes and novel intermediates for their preparation, pharmaceutical compositions containing them and with their use in medicine, particularly in the prophylaxis and treatment of hyperlipidermic conditions and associated diseases, such as atherosclerosis.
L'invention concerne de nouveaux composés hypolipidémiques de formule (I), dans laquelle R?1¿ représente H ou méthyle. L'invention concerne également des sels, des produits de solvatation, ou des dérivés physiologiquement fonctionnels de ces composés, des processus et des nouveaux intermédiaires pour la préparation de ces composés, ainsi que des compositions pharmaceutiques contenant ces composés. L'invention concerne enfin leur utilisation en médecine, notamment pour traiter et prévenir les états hyperlipidémiques et maladies associées, par exemple l'athérosclérose.
Glaxo Group Limited
Swabey Ogilvy Renault
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