Hyposensitization agent

Details Hyposensitization agent Hyposensitization agent

A - Human Necessities

61

K

167/129, 530/15.

A61K 39/36 (2006.01) A61K 47/48 (2006.01)

Patent

CA 1333256

A novel hyposensitization agent was prepared by covalently attaching a saccharide, e.g. homo- and hetero- glycans, for example, starch, amylose, dextran, polysucrose, pullulan, elsinan, curdlan, gum arabic, gum tragacanth, guar gum, xanthan gum, carrageenan, pectin, cellulose, glucomannan, chitosan, and lipopolysaccharide, and their derivatives and partial hydrolysates to, a cedar pollen allergen. The hypo- sensitization agent can be administered to a cedar pollinosis patient without fear of eliciting anaphylaxis and allergy within a shortened hyposensitization period because the hyposensitization agent much more enhances the producibilities of immunoglobulin G and M antibodies which are specific to intact cedar pollen allergen, but extremely reduces the producibility of immunoglobulin E antibody which is specific to the allergen and responsible for anaphylaxis and allergy.

576549

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