Hypoxia inducible factors and uses thereof for inducing...

Details Hypoxia inducible factors and uses thereof for inducing... Hypoxia inducible factors and uses thereof for inducing...

C - Chemistry, Metallurgy

12

N

C12N 15/18 (2006.01) A01K 67/027 (2006.01) A61K 31/7088 (2006.01) A61K 38/18 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C07K 14/515 (2006.01) C07K 16/22 (2006.01) C12N 15/11 (2006.01) C12N 15/86 (2006.01) C12P 21/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/48 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2447958

This invention provides HIF-3.alpha. nucleic acid and sequences. Also provided are methods for using HIF-3.alpha. nucleis acids, proteins, fragments, antibodies probes, and cells, to characterize HIF-3.alpha., modulate HIF- 3.alpha. cellular levels, induce angiogenesis, improve muscular functions, and treat coronary and cardiac diseases in mammals.

L'invention concerne l'acide nucléique et les séquences du facteur de l'hypoxie HIF-3.alpha.. Elle concerne en outre les utilisations des acides nucléiques, protéines, fragments, anticorps, sonde et cellules de HIF-3.alpha., pour la caractérisation de HIF-3.alpha., la modulation des taux cellulaires de HIF-3.alpha., l'activation de l'angiogenèse, l'amélioration des fonctions musculaires et le traitement des maladie coronaires et cardiaques chez les mammifères.

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