I-superfamily conotoxins

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 38/17 (2006.01) A61P 21/00 (2006.01) A61P 25/00 (2006.01) A61P 29/00 (2006.01) C07K 14/435 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2412077

The invention relates to relatively short peptides (termed I-conotoxins herein), about 30-50 residues in length, which are naturally available in minute amounts in the venom of the cone snails or analogous to the naturally available peptides, and which preferably include four disulfide bonds.

Cette invention se rapporte à des peptides relativement courts (appelés ici conotoxines I), d'une longueur d'environ 30 à 50 résidus, qui sont disponibles dans la nature en quantités minimes dans le venin des escargots marins dits cônes, ou à des analogues de ces peptides disponibles dans la nature, et qui contiennent de préférence quatre liaisons disulfure.

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