G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/58 (2006.01) C07K 5/103 (2006.01) G01N 33/53 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2449168
Assays are disclosed for identifying peptides and peptidomimetics for promoting apotosis in cells, through a pathway involving the Inhibitor of Apoptosis Proteins (IAPs), exemplified by XIAP, and the mitochondrial protein Smac/DIABOLO (hereinafter Smac) and homologs thereof. Also disclosed are IAP- binding peptides and peptidomimetics identified through the use of the assay.
La présente invention concerne des dosages permettant d'identifier des peptides et des peptidomimétiques destinés à favoriser l'apoptose de cellules, via un passage dans lequel intervient l'inhibiteur de protéines d'apoptose (IAP), illustré par XIAP, les protéines de mitochondrie Smac/DIABOLO (dénommée Smac) et des homologues de celles-ci. Cette invention concerne aussi des peptides et des peptidomimétiques se liant à l'inhibiteur IAP identifiés à l'aide de ce dosage.
Case Martin
Kipp Rachel A.
Mclendon George
Shi Yigong
Gowling Lafleur Henderson Llp
The Trustees Of Princeton University
LandOfFree
Iap binding peptides and assays for identifying compounds... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Iap binding peptides and assays for identifying compounds..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Iap binding peptides and assays for identifying compounds... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1826241