C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/12 (2006.01) A61K 31/40 (2006.01) A61P 35/00 (2006.01) C07D 401/14 (2006.01) C07D 403/14 (2006.01) C07D 409/14 (2006.01) C12Q 1/00 (2006.01) G01N 33/566 (2006.01) G01N 33/567 (2006.01) G01N 33/58 (2006.01)
Patent
CA 2652455
The present invention discloses an isomer, enantiomer, diastereoisomer, tautomer, prodrug, pharmaceutically acceptable salt of a compound of formula I and pharmaceutical compositions thereof useful in modulating IAP function via preventing binding of a BIR binding protein to an IAP BIR domain and in treating proliferative diseases such as cancer Also, disclosed is a compound of formula I labeled with a detectable label or affinity tag useful as a probe in identifying compounds that bind to an IAP BIR domain.
La présente invention concerne un isomère, énantiomère, diastéréoisomère, tautomère, promédicament, sel pharmaceutiquement acceptable d'un composé de formule I et des compositions pharmaceutiques à base de ceux-ci, utiles pour moduler la fonction IAP en empêchant la liaison d'une protéine de liaison BIR à un domaine IAP BIR et pour traiter des maladies prolifératives telles que le cancer. L'invention concerne également un composé de formule I marqué par un marqueur détectable ou un marqueur d'affinité utile comme sonde pour identifier des composés qui se lient à un domaine IAP BIR.
Boudreault Alain
Bureau Patrick
Jaquith James
Jarvis Scott
Laurent Alain
Aegera Therapeutics Inc.
Pharmascience Inc.
Ridout & Maybee Llp
LandOfFree
Iap bir domain binding compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Iap bir domain binding compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Iap bir domain binding compounds will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1770166