Ibandronate regimen for treating metastatic bone pain

A - Human Necessities – 61 – K

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Details

A61K 31/663 (2006.01) A61P 25/04 (2006.01) A61P 29/00 (2006.01) A61P 35/04 (2006.01)

Patent

CA 2641384

Disclosed is an improved dosing regimen for treating pain associated with metastatic bone disease comprising the quick administration of an IV loading dose of ibandronate followed by an oral or intravenous (IV) maintenance dosing regimen. This regimen provides desirable therapeutic effects, including fast onset of pain relief, with a tolerable level of toxicity and is preferable for patient compliance.

La présente invention concerne un procédé amélioré de traitement de la douleur associée à une maladie osseuse métastatique comprenant l'administration rapide d'une dose d'attaque d'IV d'ibandronate suivie d'un régime de dose de maintenance par voie orale ou intraveineuse (IV). Ce procédé fournit des effets thérapeutiques désirables, y compris l'émergence rapide du soulagement de la douleur, avec un niveau tolérable de toxicité; il est préférable pour l'observance du patient.

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