Ibdv vp2 epitope recognised by virus neutralising and...

C - Chemistry – Metallurgy – 12 – N

Patent

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167/130, 530/15.

C12N 15/34 (2006.01) A61K 39/12 (2006.01) C07K 14/005 (2006.01)

Patent

CA 1339265

A recombinant DNA molecule comprising a nucleotide sequence coding for a conformational epitope of the VP2 polypeptide of IBDV. In particular, a DNA molecule comprising a sequence which substantially corresponds to the AccI-SpeI fragment,and optionally the ScaI-XhoI fragment, of the IBDV genome segment coding for the VP2 polypeptide. Synthetic peptides or polypeptides, including fused polypeptides, prepared by expression of host cells containing these DNA molecules are also disclosed, as well as compositions for stimulating an immune response against IBDV comprising at least one such synthetic peptide or polypeptides.

570428

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