Ibuprofen-antitussive combinations

Details Ibuprofen-antitussive combinations Ibuprofen-antitussive combinations

A - Human Necessities

61

K

A61K 31/19 (2006.01) A61K 31/485 (2006.01)

Patent

CA 2107332

2107332 9217177 PCTABS00016 This invention relates to pharmaceutical compositions for use in the treatment of pain and inflammation and the relief of cough and cold symptoms in a mammalian organism, said composition comprising: (i) an analgesically and anti-inflammatory effective amount of (S)-ibuprofen, or a salt thereof, substantially free of (R)-ibuprofen; and (ii) an antitussively effective amount of at least one antitussive agent selected from codeine, hydrocodone, caramiphen, carbetapentane, or dextromethorphan, or a therapeutically active stereoisomer thereof substantially free of its other stereoisomers and optionally (iii) a therapeutically effective amount of at least one expectorant selected from guaicolsulfonate, guaifenesin, guaiacol, or terpin; or a pharmaceutically acceptable salt thereof.

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