Ibuprofen-caffine combinations

A - Human Necessities – 61 – K

Patent

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A61K 31/52 (2006.01) A61K 31/195 (2006.01)

Patent

CA 2144152

This invention relates to pharmaceutical compositions for use in the treatment of pain and inflammation in mammals, in- cluding humans, by administering compositions comprising (i) an analgesically and anti-inflammatory effective amount of a salt of (S)-ibuprofen substantially free of (R)-ibuprofen wherein the salt is selected from (S)-ibuprofen-(S)-lysine and (S)-ibuprofen- (R)-lysine; and (ii) an amount effective in the enhancement of pain relief of caffeine.

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