A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/28 (2006.01) A61K 31/192 (2006.01)
Patent
CA 2667207
The invention relates to an immediate release tablet capable of being chewed or disintegrated in the oral cavity, which comprises a plurality of particles in a matrix. The particles contain an active ingredient, such as ibuprofen, and a first water soluble acid having a solubility greater than about 10 g/100mL water at 20°C; and the matrix contains a second water soluble acid having a solubility less than about 5 g/100mL water at 20°C.
L'invention concerne un comprimé à libération immédiate qui peut être mastiqué ou désagrégé dans la cavité orale et qui comprend de nombreuses particules dans une matrice. Les particules contiennent un ingrédient actif, par exemple l'ibuprofène, et un premier acide soluble dans l'eau, dont la solubilité est supérieure à environ 10g/100 ml à 20°C, et la matrice contient un deuxième acide soluble dans l'eau, dont la solubilité est inférieure à environ 5 g/100 ml d'eau à 20°C.
Mcneil-Ppc Inc.
Smart & Biggar
LandOfFree
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