Ibuprofen-decongestant combinations

A - Human Necessities – 61 – K

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A61K 31/19 (2006.01) A61K 31/415 (2006.01)

Patent

CA 2107331

2107331 9217171 PCTABS00016 This invention relates to pharmaceutical compositions for use in the treatment of pain and inflammation and the relief of nasal congestion and sinus pressure in a mammalian organism, said composition comprising: (i) an analgesically and anti-inflammatory effective amount of (S)-ibuprofen, or a salt thereof, substantially free of (R)-ibuprofen; and (ii) a sympathomimetically effective amount of at least one of the sympathomimetic amines selected from phenylephrine, phenylpropanolamine, pseudoephedrine, oxymetazoline, ephinephrine, naphazoline, xylometazoline, propylhexedrine, levo-desoxyephedrine or a therapeutically active stereoisomer thereof substantially free of its other stereoisomers or a pharmaceutically acceptable salt thereof.

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