Ibuprofen p-hydroxybenzaldehyde semicarbazone ester

Details Ibuprofen p-hydroxybenzaldehyde semicarbazone ester Ibuprofen p-hydroxybenzaldehyde semicarbazone ester

C - Chemistry, Metallurgy

07

C

260/477.5

C07C 281/14 (2006.01)

Patent

CA 1088095

ABSTRACT OF THE DISCLOSURE Ibuprofen p-hydroxybenzaldehyde semicarbazone ester having the formula 11: Image 11 was prepared from the free acid, ibuprofen [+2-(p-isobutyl- phenyl)propionic acid] (1). The ester 11 above has the anti-inflammatory activity of the free acid, but in contradistinction to it, it has a pleasant taste, suitable for oral administration such as uncoated tablets, suspensions or syrups, for the treatment of inflammatory conditions, particularly arthritis. -1-

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