Ibuprofen thioesters as inhibitors of nf-kb-dependent pain...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/19 (2006.01) A61K 31/192 (2006.01) A61K 31/70 (2006.01)

Patent

CA 2287501

The invention relates to medicaments containing Co-A thioesters of arylpropionic acids, arylacetic acids or acetylsalicylates, R-ibuprofen or ibuprofen racemates with up to 49 % S-ibuprofen or derivatives of the above- mentioned compounds, which are metabolized in an analog manner in the organism. According to the invention, said medicaments are used to indicate acute and/or chronic pain and all types of inflammations and to treat all other symptoms of inflammatory processes.

L'invention concerne des médicaments contenant des CoA-thioesters d'acides arylpropioniques, d'acides arylacétiques ou acétylsalicylates, du R-ibuprofène ou des racémates d'ibuprofène, comportant jusqu'à 49 % de S-ibuprofène ou des dérivés des composés précités, qui sont métabolisés dans l'organisme de manière similaire. Selon l'invention, ces médicaments s'utilisent pour les indications de douleurs et d'inflammations aiguës et/ou chroniques, de toute origine, ainsi que pour lutter contre tous les autres symptômes de processus inflammatoires.

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