Identification and characterization of function-blocking...

Details Identification and characterization of function-blocking... Identification and characterization of function-blocking...

C - Chemistry, Metallurgy

12

N

C12N 15/13 (2006.01) A01K 67/00 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61P 35/00 (2006.01) C07K 14/00 (2006.01) C07K 16/30 (2006.01) C07K 16/46 (2006.01) C07K 19/00 (2006.01) C12N 5/10 (2006.01) C12N 15/70 (2006.01) G01N 33/53 (2006.01) G01N 33/563 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2628552

The invention relates to recombinant polypeptides, in particular antibodies or antibody fragments, which are able to bind the ED-B isoform of fibronectin and block the function thereof. Further diagnostic and pharmaceutical application of the polypeptides of the invention is also disclosed.

L~invention concerne des polypeptides recombinants, notamment des anticorps ou des fragments d~anticorps, se liant à l'isoforme ED-B de la fibronectine et en bloquant le fonctionnement. L~invention concerne également l~application pharmaceutique et en matière de diagnostic des polypeptides selon l~invention.

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