Identification and characterization of proteins using new...

G - Physics – 01 – N

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G01N 33/50 (2006.01)

Patent

CA 2554708

A method of selecting a set of candidate polypeptides for a sample polypeptide that includes a first refining of a collection of candidate polypeptides from differences in mass of fragments of the sample polypeptide produced by mass spectrometry and a second refining of the collection of candidate polypeptides from the absolute mass of the sample polypeptide and the absolute mass of the fragments.

Une méthode de sélection d'un groupe de polypeptides candidats pour un polypeptide d'un échantillon consiste à affiner une première fois un ensemble de polypeptides candidats sur la base des différences de masse de fragments du polypeptide d'échantillon produites par spectrométrie de masse et à affiner une deuxième fois l'ensemble de polypeptides candidats sur la base de la masse absolue du polypeptide d'échantillon et de la masse absolue des fragments.

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