C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/43 (2006.01) C12N 15/82 (2006.01)
Patent
CA 2637665
The invention relates to identifying and evaluating target coding sequences for control of plant parasitic nematodes by inhibiting one or more biological functions, and their use. The invention provides methods and compositions for identification of such sequences and for the control of a plant-parasitic nematode population. By feeding one or more recombinant double stranded RNA molecules provided by the invention to the nematode, a reduction in disease may be obtained through suppression of nematode gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, and the plant cells and plants obtained thereby.
La présente invention consiste à identifier et évaluer les séquences de codage cible afin de lutter contre les nématodes parasites de plantes en inhibant une ou plusieurs fonctions biologiques, et concerne leur utilisation. En outre, l'invention se rapporte aux procédés et aux compositions permettant d'identifier de telles séquences et de lutter contre une population de nématodes parasites de plantes. On peut enrayer la maladie grâce à la suppression de l'expression d'un gène de nématode et ce, en donnant au nématode une ou plusieurs molécules d'ARN double brin recombiné obtenues dans le cadre de cette invention. L'invention porte aussi sur des procédés permettant de produire des plantes transgéniques qui expriment les molécules d'ARN double brin, ainsi que sur les cellules végétales et les plantes ainsi obtenues.
Boukharov Andrey A.
Du Zijin
Guo Liang
Hresko Michelle C.
Kovalic David K.
Mcfadden Fincham
Monsanto Technology Llc
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