A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
195/140, 260/212
A61K 39/10 (2006.01) A61K 39/395 (2006.01) C07K 16/12 (2006.01) C12P 19/04 (2006.01) G01N 33/569 (2006.01)
Patent
CA 1212051
TITLE IDENTIFICATION OF BRUCELLA ABORTUS AND BRUCELLOSIS INFECTION INVENTOR David R. Bundle Malcolm B. Perry John W. Cherwonogrodzky J. Robert Duncan Martine G. Caroff ABSTRACT OF THE DISCLOSURE The antigenic O-chain polysaccharides from Brucella abortus and Yersinia enterocolitica serotype 0:9 have structure, i.e. 1-2 linked 4,6-dideoxy-4-formamido-.alpha.-D-mannopyranosyl units. The antigen is more readily isolated from the Yersinia and may be chemically modified to have a hydrophobic moiety attached thereto. The antigen can be adsorbed or coupled to carriers suitable for immunoassay use such as ELISA and RIA. A monoclonal antibody capable of specifically binding to B. abortus and Y enterocolitica, has been produced. Assay procedures and kits there- for, are described.
448768
Bundle David R.
Caroff Martine G.
Cherwonogrodzky John W.
Duncan J. Robert
Perry Malcolm B.
National Research Council Of Canada
Thomson Alan A.
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