G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/574 (2006.01)
Patent
CA 2557438
The claimed invention describes methods to diagnose or aid in the diagnosis of cancer. The claimed methods are based on the identification of biomarkers which are particularly well suited to discriminate between cancer subjects and healthy subjects. These biomarkers were identified using a unique and novel screening method described herein. The biomarkers identified herein can also be used in the prognosis and monitoring of cancer. The invention comprises the use of leptin, prolactin, OPN and IGF-II for diagnosing, prognosis and monitoring of ovarian cancer.
La présente invention se rapporte à des méthodes permettant de diagnostiquer un cancer ou de contribuer au diagnostic d'un cancer. Les méthodes selon l'invention se fondent sur l'identification de biomarqueurs qui sont particulièrement efficaces pour distinguer les sujets cancéreux des sujets sains. Lesdits biomarqueurs ont été identifiés à l'aide d'un procédé de criblage nouveau et unique faisant également l'objet de l'invention. Les biomarqueurs selon l'invention peuvent également être utilisés pour effectuer le pronostic et la surveillance d'un cancer. L'invention fait appel à la leptine, la prolactine, l'OPN et l'IGF-II pour effectuer le diagnostic, le pronostic et la surveillance d'un cancer de l'ovaire.
Bray-Ward Patricia
Mor Gil G.
Ward David C.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Yale University
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