Identification of compounds for inhibiting mta/adohcy...

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/34 (2006.01) C12N 9/24 (2006.01)

Patent

CA 2390971

The invention includes the 3D structure of MTA/AdoHcy nucleosidases. It also includes methods of identifying compounds that modulate MTA/AdoHcy nucleosidase activity by producing a compound that interacts with all or part of the 3D structure of MTA/AdoHcy nucleosidase or a fragment or derivative thereof and which thereby modulates MTA/AdoHcy nucleosidase activity.

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