C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/55 (2006.01) A61K 38/46 (2006.01) A61P 35/00 (2006.01) C07K 1/00 (2006.01) C07K 14/47 (2006.01) C07K 16/40 (2006.01) C07K 17/00 (2006.01) C08L 91/00 (2006.01) C12N 9/16 (2006.01) C12N 9/96 (2006.01) C12N 11/00 (2006.01) C12N 15/12 (2006.01)
Patent
CA 2752590
An isolated human phosphatase and tensin homolog long polypeptide (PTEN-long) comprising SEQ ID NO: 1, fragments and analogues thereof, nucleic acids encoding such and compositions comprising such are provided. Methods to inhibit angiogenesis in a solid tumor, treat a solid tumor, and inhibit growth of a solid tumor using PTEN-long, fragments and analogues thereof, are provided.
L'invention porte sur une phosphatase humaine isolée et sur un polypeptide long homologue de la tensine (PTEN-long) comprenant SEQ ID N° : 1, sur des fragments et analogues de ceux-ci, sur des acides nucléiques codant pour ceux-ci et sur des compositions les comprenant. L'invention porte sur des procédés pour inhiber l'angiogenèse dans une tumeur solide, traiter une tumeur solide et inhiber la croissance d'une tumeur solide à l'aide de PTEN long, de fragments et d'analogues de celui-ci.
Benoit & Cote Associes Inc.
The Trustees Of Columbia University In The City Of New York
LandOfFree
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