Identification of genetic alterations that modulate drug...

Details Identification of genetic alterations that modulate drug... Identification of genetic alterations that modulate drug...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) A61K 31/713 (2006.01) A61K 45/00 (2006.01) A61P 35/00 (2006.01) C12Q 1/02 (2006.01) C40B 40/06 (2006.01) G01N 33/68 (2006.01) C12N 15/11 (2006.01)

Patent

CA 2680593

This invention features methods of identifying genetic alterations that can modulate cancer cells' sensitivity to an anti-cancer drug. Information on such genetic alterations can be used to predict cancer therapeutic outcomes and to stratify patient populations to maximize therapeutic efficacy.

La présente invention concerne des procédés d'identification de modifications génétiques qui peuvent moduler la sensibilité de cellules cancéreuses à un médicament anticancéreux. Des informations sur de telles modifications génétiques peuvent être utilisées pour prédire des résultats thérapeutiques sur cancer et pour stratifier des populations de patients afin de maximiser une efficacité thérapeutique.

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