C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) C07K 14/505 (2006.01) C12N 15/10 (2006.01) C12N 15/62 (2006.01) C12N 15/85 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2298412
The invention relates to methods for the selection of human cells for the preparation of human proteins by endogenic gene activation in order to produce human proteins in economical yields and in a form which is suitable for the production of a pharmaceutical preparation. The invention furthermore relates to a method for the production of human proteins in a cell line identified in this manner.
L'invention concerne un procédé de sélection de cellules humaines devant servir à la préparation de protéines humaines par activation génique endogène, en vue de produire des protéines humaines avec des rendements économiques et sous une forme appropriée pour l'obtention d'une préparation pharmaceutique. L'invention comprend également un procédé de production de protéines humaines dans une lignée cellulaire identifiée de cette manière.
Brandt Michael
Franze Reinhard
Pessara Ulrich
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Roche Diagnostics Gmbh
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